Journal: Translational Oncology

Article Title: Multi-Spectral Fluorescence Imaging of Colon Dysplasia In Vivo Using a Multi-Spectral Endoscopy System 1

doi: 10.1016/j.tranon.2018.10.006

Figure Lengend Snippet: Setup of multi-spectral endoscope and phantom study. (A) Design and fabrication of multi-spectral endoscope. Detection of white light image was performed by CCD camera and fluorescent image by Nuance camera. The collected images or fluorescence signal is divided in beam splitter and passes through each lens in front of two CCD camera. The excitation light which is generated from xenon lamp goes into endoscopic channel and excites fluorophores of fluorescent probes. (B) Demonstration of multiplexing on phantom study with a polyethylene mock-up tube, which was attached to metal ring (Left upper). (Lower) Each unmixed signal is seen with (Left lower) and without (Right lower) pseudo-color. The bare-eyed reflection image is shown in the figure (Reflection RGB, middle lower). The graph represents emission spectra of each dyes (Upper Right).

Article Snippet: The imaging system is composed of a 0°cysto-urethroscope (Karl Storz, Tuttlingen, Germany), multi-spectral imaging system (Nuance FX, PerkinElmer, Hopkinton, MA), sensitive color charge-coupled device (CCD) camera (QIClick, QImaging, Surrey, BC, Canada), and achromatic lenses as depicted A .

Techniques: Fluorescence, Generated, Multiplexing